VITAMIN B COMPLEX: A REVIEW of Different Types and Activities

Document Type : Review Articles.

Authors

1 Pharmaceutical Chemistry, Faculty of Pharmacy, Misr University for science and Technology

2 Pharmacy, Misr University for Science and Technology

3 MYST

4 Must

5 must

6 2220000000

7 other

8 department of pharmaceutical chemistry, faculty of pharmacy, cairo university

Abstract

B complex vitamins are a group of water-soluble compounds essential for numerous physiological functions in the human body. Comprising eight distinct members, including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin), these vitamins play pivotal roles in energy metabolism, DNA synthesis, and red blood cell formation. Thiamine, for instance, is crucial for converting carbohydrates into energy, while riboflavin supports tissue maintenance and growth. Niacin contributes to skin health and aids in the metabolism of fats. Pantothenic acid is essential for synthesizing fatty acids and amino acids, while pyridoxine supports neurotransmitter function. Biotin is vital for skin, hair, and nail health, and folate is integral for DNA synthesis and cell division. Cobalamin, often associated with nerve function, assists in the formation of red blood cells. These vitamins are commonly found in a variety of foods, and their deficiency can lead to various health issues, including anemia, fatigue, and neurological problems. We discuss the pharmacological activities, metabolism, and Structure-Activity Relationship (SAR), as well as the derivatives and uses of vitamins B1, B2, B3, B5 and B12.

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